SS-31 (Elamipretide)

SS-31 improves mitochondrial function.

Research shows SS-31 enhances mitochondrial efficiency by stabilizing cardiolipin, leading to improved ATP production and cellular energy output.

SS-31 reduces oxidative stress.

Studies indicate significant reductions in reactive oxygen species (ROS), helping protect cells from oxidative damage.

SS-31 supports muscle function and endurance.

Preclinical research demonstrates improved muscle performance and reduced fatigue through enhanced mitochondrial energy production.

SS-31 may improve cardiovascular health.

Studies suggest improved cardiac efficiency and protection against mitochondrial dysfunction in heart tissue.

SS-31 enhances recovery from cellular stress.

Research indicates faster recovery following oxidative or metabolic stress due to preserved mitochondrial integrity.

SS-31 supports aging-related research.

By improving mitochondrial health, SS-31 is widely studied in pathways associated with aging and cellular longevity.

SS-31 improves metabolic efficiency.

Enhanced mitochondrial performance leads to better energy utilization and reduced metabolic strain.

SS-31 protects against cell death.

Research shows reduced apoptosis in stressed cells, supporting tissue preservation.

SS-31 supports neuroprotective pathways.

Preclinical studies suggest benefits in maintaining neuronal function through improved mitochondrial stability.

SS-31 enhances overall cellular resilience.

By optimizing mitochondrial performance, SS-31 helps cells better withstand environmental and metabolic stressors.

SS-31 (Elamipretide) is a mitochondria-targeting peptide that selectively interacts with cardiolipin, a key phospholipid located in the inner mitochondrial membrane. Below is a detailed explanation of its action:

Targeting of Mitochondrial Membranes: SS-31 selectively penetrates cells and localizes within mitochondria, where it binds to cardiolipin. This interaction helps stabilize the structure of the inner mitochondrial membrane.

Stabilization of Electron Transport Chain (ETC): By binding to cardiolipin, SS-31 supports the integrity of the electron transport chain, improving the efficiency of oxidative phosphorylation and ATP production.

Reduction of Reactive Oxygen Species (ROS): SS-31 helps reduce excessive production of reactive oxygen species by improving electron flow within the mitochondria, minimizing oxidative stress and cellular damage.

Enhancement of Cellular Energy Production: Through improved mitochondrial efficiency, SS-31 increases ATP generation, supporting overall cellular energy demands and function.

Protection Against Cellular Stress: The peptide helps preserve mitochondrial function under conditions of stress, reducing apoptosis (cell death) and supporting tissue integrity.

Systemic Cellular Effects: Improved mitochondrial performance influences multiple systems, including muscle function, cardiovascular health, and metabolic efficiency, making SS-31 a key focus in aging and performance research.

Intended Use: SS-31 (Elamipretide) is designed for Research Purposes only.

Storage: Store in a cool, dry place away from direct sunlight. Once reconstituted, keep refrigerated at 2–8°C.

Solubility: Reconstitute with bacteriostatic water or appropriate research-grade solvent.

Shelf Life: The lyophilized form has a shelf life of up to 24 months when properly stored. Once reconstituted, refrigerate and use within 4–6 weeks.

Handling: Ensure sterile techniques are used to maintain product integrity during research.